Detection of Multiple Sclerosis Lesions in Supra- and Infra-Tentorial Anatomical Regions by Double Inversion Recovery, Flair, and T2 MRI Sequences: A Comparative Study in Iraqi Patients

Mahmood Mishaal Mohamed; Maryam Issa Al-Ani; Gheyath Al Gawwam; Murtadha Hussein Alrubaye; Ahmed Al-Imam

doi:10.54133/ajms.v5i1S.357

Authors

Mahmood Mishaal Mohamed Department of Anatomy and Cellular Biology, College of Medicine, University of Baghdad, Baghdad, Iraq https://orcid.org/0000-0002-3635-7891
Maryam Issa Al-Ani Department of General Surgery, College of Medicine, University of Baghdad, Baghdad, Iraq
Gheyath Al Gawwam Department of Medicine, College of Medicine, University of Baghdad, Baghdad, Iraq
Murtadha Hussein Alrubaye Regional Hospital Gødstrup, The Hospital Park 15, 7400 Herning, Denmark
Ahmed Al-Imam Department of Anatomy and Cellular Biology, College of Medicine, University of Baghdad, Baghdad 10047, Iraq; Alumni Ambassador, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AD, UK https://orcid.org/0000-0003-1846-9424

DOI:

https://doi.org/10.54133/ajms.v5i1S.357

Keywords:

Double inversion recovery sequence, FLAIR sequence, Multiple sclerosis, T2 weighted image

Abstract

Background: In young adults, multiple sclerosis is a prevalent chronic inflammatory demyelinating condition. It is characterized by white matter affection, but many individuals also have significant gray matter involvement. A double-inversion recovery pulse (DIR) pattern was recently proposed to improve the visibility of multiple sclerosis lesions. Objective: To find out how well a DIR sequence, FLAIR, and T2-weighted pulse sequences can find MS lesions in the supratentorial and infratentorial regions. Methods: A total of 37 patients with established diagnoses of multiple sclerosis were included in this cross-sectional study. Brain MRI was done using double inversion recovery, T2, and FLAIR sequences. The number of lesions was counted and compared in the three sequences. Results: The DIR sequence detected more infratentorial lesions when compared to the T2 and FLAIR sequences. In the supratentorial region, DIR detected more lesions than T2 and FLAIR. Conclusion: The DIR sequence is highly superior to both the T2 and FLAIR sequences in depicting the lesions, regardless of their anatomical distribution. Moreover, the DIR sequence detected more multiple sclerosis lesions in the infratentorial region than the traditional T2W and FLAIR sequences.

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