Bone Gutter and Myoosseous Muscle Flap in Chronic Femoral Osteomyelitis in Adults: A 2-Year Prospective Case Series
DOI:
https://doi.org/10.54133/ajms.v9i1.2130Keywords:
Bone Gutter, Chronic Osteomyelitis, Femur, Myoosseous muscle flapAbstract
Background: Chronic osteomyelitis of the femur is a complex orthopedic challenge that needs comprehensive surgical and antibiotic treatment. Bone guttering with myoosseous muscle flap coverage offers promising outcomes in controlling infection and enhancing tissue healing. Objective: To assess the effectiveness of bone gutter and myoosseous muscle flap in adult males with chronic femur osteomyelitis. Methods: A prospective case series study enrolled 24 male patients with chronic femoral shaft osteomyelitis. (62.5%) Cases were managed by bone guttering, myoosseous muscle flap, or implant removal followed by the same procedure (37.5%). Antibiotics were given based on culture and sensitivity, and the Cierny-Mader classification was used for staging. The clinical outcome was assessed by infection resolution, wound healing, and recurrence rates over 24 months of follow-up. Results: The mean age was 29.00±6.56 years. All cases presented with discharging sinus, Staphylococcus aureus (50.0%), and Streptococcus (25.0%), which were the most frequently reported microorganisms. 50.0% of cases were treated with fusidic acid, followed by Augmentin (25%) for 6 weeks. After 2 years of follow-up, complete infection resolution and healing were achieved (100.0%). Conclusions: Bone guttering with myoosseous muscle flap is a simple, reproducible, and highly effective management strategy for chronic femoral osteomyelitis. The approach achieved complete bone infection control when combined with targeted antibiotics. Larger multicentric studies are recommended to generalize these findings.
Downloads
References
Panteli M, Giannoudis PV. Chronic osteomyelitis: what the surgeon needs to know. EFORT Open Rev. 2016;1(5):128-135. doi: 10. 1302/2058-5241.1.000017. DOI: https://doi.org/10.1302/2058-5241.1.000017
Mohammed YR. Spontaneous correction of extreme degree femur ante–version in developmental dysplasia of the hip. Kirkuk J Med Sci. 2023;11(1). doi: 10.32894/kjms.2022.137425.1048. DOI: https://doi.org/10.32894/kjms.2022.137425.1048
Schmitt SK. Osteomyelitis. Infect Dis Clin North Am. 2017;31(2):325-338. doi: 10.1016/j.idc.2017.01.010. DOI: https://doi.org/10.1016/j.idc.2017.01.010
Hatzenbuehler J, Pulling TJ. Diagnosis and management of osteomyelitis. Am Fam Physician. 2011;84(9):1027-1033. PMID: 22046943.
Roomi AB, Mahdi Salih AH, Noori SD, Nori W, Tariq S. Evaluation of bone mineral density, serum osteocalcin, and osteopontin levels in postmenopausal women with type 2 diabetes mellitus, with/without osteoporosis. J Osteoporosis. 2022;2022(1):1437061. doi: 10.1155/2022/1437061. DOI: https://doi.org/10.1155/2022/1437061
Khalid Abdulqader S, Nori W, Akram N, Al-Kinani M. Radiological modalities for the assessment of fetal growth restriction: A comprehensive review. AL-Kindy Coll Med J. 2024;20(1):4-13. doi: 10.47723/nz221421. DOI: https://doi.org/10.47723/nz221421
Gilliéron P, Boillat-Blanco N, Nicod Lalonde M, Becce F, Omoumi P, Prior JO, et al. Diagnosis and management of chronic osteomyelitis of long bones in adults. Rev Med Suisse. 2021;17(763):2194-2200. PMID: 34910406. DOI: https://doi.org/10.53738/REVMED.2021.17.763.2194
Kanakaris NK, Giannoudis PV. Biofilm and its implications postfracture fixation: All I need to know. OTA Int. 2021;4(3S):e107. doi: 10.1097/OI9.0000000000000107. DOI: https://doi.org/10.1097/OI9.0000000000000107
Herrera LA, Benítez‐Bribiesca L, Mohar A, Ostrosky‐Wegman P. Role of infectious diseases in human carcinogenesis. Environ Mol Mutagenesis. 2005;45(2‐3):284-303. doi: 10.1002/em.20122. DOI: https://doi.org/10.1002/em.20122
Hofstee MI, Muthukrishnan G, Atkins GJ, Riool M, Thompson K, Morgenstern M, et al. Current concepts of osteomyelitis: From pathologic mechanisms to advanced research methods. Am J Pathol. 2020;190:1151e1163 doi: 10.1016/j.ajpath.2020.02.007. DOI: https://doi.org/10.1016/j.ajpath.2020.02.007
Carpintero P, Caeiro JR, Carpintero R, Morales A, Silva S, Mesa M. Complications of hip fractures: A review. World J Orthoped. 2014;5(4):402. doi: 10.5312/wjo.v5.i4.402. DOI: https://doi.org/10.5312/wjo.v5.i4.402
Pande KC. Optimal management of chronic osteomyelitis: current perspectives. Orthoped Res Rev. 2015:71-81. doi: 10.2147/ORR.S50753.
Lari A, Esmaeil A, Marples M, Watts A, Pincher B, Sharma H. Single versus two-stage management of long-bone chronic osteomyelitis in adults: a systematic review and meta-analysis. J Orthop Surg Res. 2024;19(1):351. doi: 10.1186/s13018-024-04832-7. DOI: https://doi.org/10.1186/s13018-024-04832-7
Behrendt D, Josten C. Osteomyelitis in adults: in consideration of soft tissue problems. Der Chirurg. 2014;85:261-272. DOI: https://doi.org/10.1007/s00104-012-2393-8
Cierny G, Mader JT, Penninck JJ. A clinical staging system for adult osteomyelitis. Clin Orthop Relat Res. 2003;414:7-24. doi: 10.1097/01.blo.0000088564.81746.62. DOI: https://doi.org/10.1097/01.blo.0000088564.81746.62
Gokalp MA, Guner S, Ceylan MF, Doğan A, Sebik A. Results of treatment of chronic osteomyelitis by gutter procedure and muscle flap transposition operation. Eur J Orthop Surg Traumatol. 2014;24(3):415-419. doi: 10.1007/s00590-013-1196-z. DOI: https://doi.org/10.1007/s00590-013-1196-z
Anthony JP, Mathes SJ, Alpert BS. The muscle flap in treating chronic lower extremity osteomyelitis: results in patients over 5 years after treatment. Plast Reconstr Surg. 1991;88(2):311-318. doi: 10.1097/00006534-199108000-00023. DOI: https://doi.org/10.1097/00006534-199108000-00023
Lok V, Bal E, Aydinok H. Long-term results of treatment including creation of a gutter and muscle transposition for chronic sclerosing osteomyelitis. Acta Orthopaedica et Traumatol Turcica. 2009;43(6):510-514. doi: 10.3944/AOTT.2009.510. DOI: https://doi.org/10.3944/AOTT.2009.510
Necmioglu S, Askar I, Lok V, Subasi M. Use of the vastus lateralis muscle flap with a grooving procedure in the surgical treatment of chronic osteomyelitis of the femur. Ann Plast Surg. 2004;53:570–576 doi: 10.1097/01.sap.0000134752.01294.d0. DOI: https://doi.org/10.1097/01.sap.0000134752.01294.d0
Fitzgerald RH, Ruttle PE, Arnold PG, Kelly PJ, Irons GB. Local muscle flaps in the treatment of chronic osteomyelitis. J Bone Joint Surg Am. 1985;67(2):175-185. PMID: 3968107. DOI: https://doi.org/10.2106/00004623-198567020-00001
Ngoí SS, Satku K, Pho RW, Kumar VP. Local muscle flaps in treating chronic osteomyelitis--the introduction of new vasculature. Injury. 1987 Sep;18(5):350-353. doi: 10.1016/0020-1383(87)90060-x. DOI: https://doi.org/10.1016/0020-1383(87)90060-X
Haidar R, Boghossain AD, Atiyeh B. Duration of post-surgical antibiotics in chronic osteomyelitis: empiric or evidence-based? Int J Infect Dis. 2010;14:e752–e758. DOI: https://doi.org/10.1016/j.ijid.2010.01.005
Calhoun JH, Manring MM. Adult osteomyelitis. Infect Dis Clin North Am. 2005;19(4):765-786. doi: 10.1016/j.idc.2005.07.009. DOI: https://doi.org/10.1016/j.idc.2005.07.009
Pande KC. Optimal management of chronic osteomyelitis: current perspectives, Orthoped Res Rev. 2015;7:71-81. doi: 10.2147/ORR.S50753. DOI: https://doi.org/10.2147/ORR.S50753
Mathes SJ. The muscle flap for management of osteomyelitis. N Engl J Med. 1982;306(5):294-295. doi: 10.1056/NEJM198202043060509. DOI: https://doi.org/10.1056/NEJM198202043060509
Ikpeme IA, Oku EO, Ngim NE, Ilori IU, Abang IE. Comparison of the outcome of treatment of chronic osteomyelitis by surgical debridement with and without local antibiotic delivery system: experience from a Nigerian Teaching Hospital. Int J Clin Med. 2013;4:313–318. doi: 10.4236/ijcm.2013.47055. DOI: https://doi.org/10.4236/ijcm.2013.47055
Ger R. Muscle transposition for treatment and prevention of chronic post-traumatic osteomyelitis of the tibia. J Bone Joint Surg Am. 1977;59(6):784-791. PMID: 332697. DOI: https://doi.org/10.2106/00004623-197759060-00012
Stolyarov EA, Soloviev AV. Transposition of muscles in the treatment of chronic osteomyelitis. Kazan Med J. 1991;72(6):423-425. doi: 10.17816/kazmj83891. DOI: https://doi.org/10.17816/kazmj83891
Shakhatreh R, Shakhatreh H. Drug review and development: Innovations, challenges, and ethical considerations. Kirkuk J Medical Sci. 2025;13(1):63-65. doi: 10.32894/kjms.2024.147350.1100. DOI: https://doi.org/10.32894/kjms.2024.147350.1100
Taha MA, Istifo NN. Evaluation of osteoporosis among epileptic patients on monotherapy. Iraqi J Pharm Sci. 2024;33(1):129-136. doi: 10.31351/vol33iss1pp129-136. DOI: https://doi.org/10.31351/vol33iss1pp129-136

Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 )

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Published by Al-Rafidain University College. This is an open access journal issued under the CC BY-NC-SA 4.0 license (https://creativecommons.org/licenses/by-nc-sa/4.0/).