Sarcopenia and Its Associated Factors among Urban Sedentary Adults in Jakarta: Evidence from a Large Multidistrict Dataset
DOI:
https://doi.org/10.54133/ajms.v11i2.3150Keywords:
Diabetes mellitus, Muscle strength, Muscle mass, Sarcopenia, Sedentary lifestyle, Urban populationAbstract
Background: Sarcopenia is a major public health concern in aging populations, particularly in urban sedentary settings, where physical inactivity and metabolic disorders contribute to muscle decline. Objective: To identify factors associated with muscle strength and muscle mass and to develop a simplified scoring system for sarcopenia in urban sedentary pre-elderly and elderly populations. Methods: A cross-sectional study was conducted using secondary data from the PRIMBON 2025 database in Jakarta. A total of 425 participants were analyzed. Sarcopenia components were assessed using AWGS criteria. Results: Male sex (OR=1.897; p=0.008), depression (OR=1.739; p=0.012), and type 2 diabetes mellitus (OR=4.923; p<0.001) were independently associated with higher odds of low muscle strength, whereas central obesity was independently associated with lower odds of low muscle strength (OR=0.519; p=0.011). Older age was strongly associated with low muscle mass (OR=2.850; p<0.001), while hypertension, obesity, and central obesity demonstrated inverse associations. ROC analysis showed moderate discrimination for muscle strength (AUC=0.690; CI=0.639–0.741) and excellent discrimination for muscle mass (AUC=0.879; 95%CI= 0.845–0.912). Conclusions: Sarcopenia in urban sedentary populations is influenced by multifactorial determinants, including demographic, psychological, and metabolic factors. The developed scoring system provides a practical tool for early screening and risk stratification, although further validation is needed.
Downloads
References
Petermann‐Rocha F, Balntzi V, Gray SR, Lara J, Ho FK, Pell JP, et al. Global prevalence of sarcopenia and severe sarcopenia: a systematic review and meta‐analysis. J Cachexia Sarcopenia Muscle. 2022;13(1):86–99. doi: 10.1002/jcsm.12783. DOI: https://doi.org/10.1002/jcsm.12783
Mahardhika GS, Hurulhanifa F, Laranti NAS, Shabrina HN, Agatri N. Diagnosis of sarcopenia in geriatrics using actigraph wGT3XBT accelerometer: A narrative review. Cermin Dunia Kedokt. 2025;52:683–688. DOI:10.55175/cdk.v52i10.1421. DOI: https://doi.org/10.55175/cdk.v52i10.1421
Mitchell WK, Williams J, Atherton P, Larvin M, Lund J, Narici M. Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength: A quantitative review. Front Physiol. 2012;3:360. doi: 10.3389/fphys.2012.00260. DOI: https://doi.org/10.3389/fphys.2012.00260
Cruz-Jentoft AJ, Sayer AA. Sarcopenia. Lancet. 2019;393(10191):2636–2646. doi: 10.1016/S0140-6736(19)31138-9. DOI: https://doi.org/10.1016/S0140-6736(19)31138-9
Wei S, Nguyen TT, Zhang Y, Ryu D, Gariani K. Sarcopenic obesity: epidemiology, pathophysiology, cardiovascular disease, mortality, and management. Front Endocrinol (Lausanne). 2023;14. doi: 10.3389/fendo.2023.1185221. DOI: https://doi.org/10.3389/fendo.2023.1185221
Gao Q, Mei F, Shang Y, Hu K, Chen F, Zhao L, et al. Global prevalence of sarcopenic obesity in older adults: A systematic review and meta-analysis. Clin Nutr. 2021;40(7):4633–4641. doi: 10.1016/j.clnu.2021.06.009. DOI: https://doi.org/10.1016/j.clnu.2021.06.009
Wagenaar CA, Dekker LH, Navis GJ. Prevalence of sarcopenic obesity and sarcopenic overweight in the general population: The lifelines cohort study. Clin Nutr. 2021;40(6):4422–4429. doi: 10.1016/j.clnu.2021.01.005. DOI: https://doi.org/10.1016/j.clnu.2021.01.005
Yang M, Hu X, Xie L, Zhang L, Zhou J, Lin J, et al. Comparing mini sarcopenia risk assessment with SARC-F for screening sarcopenia in community-dwelling older adults. J Am Med Dir Assoc. 2019;20(1):53–57. doi: 10.1016/j.jamda.2018.04.012. DOI: https://doi.org/10.1016/j.jamda.2018.04.012
Malmstrom TK, Miller DK, Simonsick EM, Ferrucci L, Morley JE. SARC-F: a symptom score to predict persons with sarcopenia at risk for poor functional outcomes. J Cachexia Sarcopenia Muscle. 2016;7(1):28-36. doi: 10.1002/jcsm.12048. DOI: https://doi.org/10.1002/jcsm.12048
Chen LK, Hsiao FY, Akishita M, Assantachai P, Lee WJ, Lim WS, et al. A focus shift from sarcopenia to muscle health in the Asian Working Group for Sarcopenia 2025 Consensus Update. Nat Aging. 2025;5(11):2164–2175. doi: 10.1038/s43587-025-01004-y. DOI: https://doi.org/10.1038/s43587-025-01004-y
Voulgaridou G, Tyrovolas S, Detopoulou P, Tsoumana D, Drakaki M, Apostolou T, et al. Diagnostic criteria and measurement techniques of sarcopenia: A critical evaluation of the up-to-date evidence. Nutrients. 2024;16(3):436. doi: 10.3390/nu16030436. DOI: https://doi.org/10.3390/nu16030436
Lu JL, Ding LY, Xu Q, Zhu SQ, Xu XY, Hua HX, et al. Screening accuracy of SARC-F for sarcopenia in the elderly: A diagnostic meta-analysis. J Nutr Health Aging. 2021;25(2):172-182. doi: 10.1007/s12603-020-1471-8. DOI: https://doi.org/10.1007/s12603-020-1471-8
Chen LK, Woo J, Assantachai P, Auyeung TW, Chou MY, Iijima K, et al. Asian working group for sarcopenia: 2019 Consensus update on sarcopenia diagnosis and treatment. J Am Med Dir Assoc. 2020;21(3):300-307.e2. doi: 10.1016/j.jamda.2019.12.012. DOI: https://doi.org/10.1016/j.jamda.2019.12.012
Bhasin S, Travison TG, Manini TM, Patel S, Pencina KM, Fielding RA, et al. Sarcopenia definition: The position statements of the sarcopenia definition and outcomes consortium. J Am Geriatr Soc. 2020;68(7):1410-1418. doi: 10.1111/jgs.16372. DOI: https://doi.org/10.1111/jgs.16372
Hanatani S, Izumiya Y, Yamamoto M, Araki S, Fujisue K, Arima Y, et al. A simple method of sarcopenia detection can predict adverse cardiovascular events in patients with abdominal obesity. Int J Obes (Lond). 2021;45(10):2214-2220. doi: 10.1038/s41366-021-00895-2. DOI: https://doi.org/10.1038/s41366-021-00895-2
Kang SY, Lim GE, Kim YK, Kim HW, Lee K, Park TJ, et al. Association between sarcopenic obesity and metabolic syndrome in postmenopausal women: A cross-sectional study based on the Korean national health and nutritional examination surveys from 2008 to 2011. J Bone Metab. 2017;24(1):9-14. doi: 10.11005/jbm.2017.24.1.9. DOI: https://doi.org/10.11005/jbm.2017.24.1.9
Aubertin-Leheudre M, Anton S, Beavers DP, Manini TM, Fielding R, Newman A, et al. Dynapenia and metabolic health in obese and nonobese adults Aged 70 years and older: The LIFE study. J Am Med Dir Assoc. 2017;18(4):312-319. doi: 10.1016/j.jamda.2016.10.001. DOI: https://doi.org/10.1016/j.jamda.2016.10.001
Bai T, Fang F, Li F, Ren Y, Hu J, Cao J. Sarcopenia is associated with hypertension in older adults: a systematic review and meta-analysis. BMC Geriatr. 2020;20(1):279. doi: 10.1186/s12877-020-01672-y. DOI: https://doi.org/10.1186/s12877-020-01672-y
Zou J, Liu Y, Tian C, Wang L, Li S, Ran J, et al. Understanding the complexity of hypertension with sarcopenia by scientometric analysis. J Multidiscip Healthc. 2024;17:6211-6228. doi: 10.2147/JMDH.S498799. DOI: https://doi.org/10.2147/JMDH.S498799
Quan Y, Wang C, Wang L, Li G. Geriatric sarcopenia is associated with hypertension: A systematic review and meta-analysis. J Clin Hypertens (Greenwich). 2023;25(9):808-816. doi: 10.1111/jch.14714. DOI: https://doi.org/10.1111/jch.14714
Han K, Park YM, Kwon HS, Ko SH, Lee SH, Yim HW, et al. Sarcopenia as a determinant of blood pressure in older Koreans: findings from the Korea National Health and Nutrition Examination Surveys (KNHANES) 2008-2010. PLoS One. 2014;9(1):e86902. doi: 10.1371/journal.pone.0086902. DOI: https://doi.org/10.1371/journal.pone.0086902
Taekema DG, Maier AB, Westendorp RG, de Craen AJ. Higher blood pressure is associated with higher handgrip strength in the oldest old. Am J Hypertens. 2011;24(1):83-89. doi: 10.1038/ajh.2010.185. DOI: https://doi.org/10.1038/ajh.2010.185
Jurdana M, Žiberna L. Sarcopenic obesity and hypertension in elderly patients: a narrative review of pathophysiology and management strategies. Ann Ist Super Sanita. 2023;59(3):231-239. doi: 10.4415/ANN_23_03_10.
Soltani S, Hashemi R, Heshmat R, Motlagh AD, Esmaillzadeh A. Association of dietary approaches to stop hypertension eating style and risk of sarcopenia. Sci Rep. 2020;10(1):19339. doi: 10.1038/s41598-020-76452-0. DOI: https://doi.org/10.1038/s41598-020-76452-0
Hashimoto Y, Kaji A, Sakai R, Hamaguchi M, Okada H, Ushigome E, et al. Sarcopenia is associated with blood pressure variability in older patients with type 2 diabetes: A cross-sectional study of the KAMOGAWA-DM cohort study. Geriatr Gerontol Int. 2018;18(9):1345-1349. doi: 10.1111/ggi.13487. DOI: https://doi.org/10.1111/ggi.13487
Ishikawa J, Toba A, Tamura Y, Araki A, Harada K. Changes in blood pressure associated with frailty and sarcopenia in elderly outpatients with cardiometabolic diseases. Geriatr Gerontol Int. 2023;23(7):506-516. doi: 10.1111/ggi.14601. DOI: https://doi.org/10.1111/ggi.14601
Marcotte-Chénard A, Oliveira B, Little JP, Candow DG. Sarcopenia and type 2 diabetes: Pathophysiology and potential therapeutic lifestyle interventions. Diabetes Metab Syndr. 2023;17(9):102835. doi: 10.1016/j.dsx.2023.102835. DOI: https://doi.org/10.1016/j.dsx.2023.102835
Alfaro-Alvarado FA, Rosas-Barrientos JV, Ocharan-Hernández ME, Díaz-Chiguer D, Vargas-De-León C. Association between sarcopenia and poor glycemic control in older adults with type 2 diabetes mellitus. Diseases. 2023;11(4):175. doi: 10.3390/diseases11040175. DOI: https://doi.org/10.3390/diseases11040175
Chung SM, Moon JS, Chang MC. Prevalence of sarcopenia and its association with diabetes: A meta-analysis of community-dwelling Asian population. Front Med (Lausanne). 2021;8:681232. doi: 10.3389/fmed.2021.681232. DOI: https://doi.org/10.3389/fmed.2021.681232
Zhang Y, Gong M, Feng XM, Yan YX. Bidirectional association between sarcopenia and diabetes: A prospective cohort study in middle-aged and elderly adults. Clin Nutr ESPEN. 2025;66:556-563. doi: 10.1016/j.clnesp.2025.02.026. DOI: https://doi.org/10.1016/j.clnesp.2025.02.026
Hettiarachchi J, Verstraeten LMG, Pacifico J, Reijnierse EM, Meskers CGM, Maier AB. Body weight and composition changes in geriatric rehabilitation are dependent on sarcopenia and malnutrition: RESORT. J Am Med Dir Assoc. 2024;25(8):105030. doi: 10.1016/j.jamda.2024.105030. DOI: https://doi.org/10.1016/j.jamda.2024.105030
Reijnierse EM, Trappenburg MC, Leter MJ, Blauw GJ, de van der Schueren MA, Meskers CG, et al. The association between parameters of malnutrition and diagnostic measures of sarcopenia in geriatric outpatients. PLoS One. 2015;10(8):e0135933. doi: 10.1371/journal.pone.0135933. DOI: https://doi.org/10.1371/journal.pone.0135933
Tonial PC, Colussi EL, Alves ALS, Stürmer J, Bettinelli LA. Prevalence of sarcopenia in elderly users of the primary health care system. Nutr Hosp. 2020;34(3):450-455. doi: 10.20960/nh.02790.
Curtis M, Swan L, Fox R, Warters A, O'Sullivan M. Associations between body mass index and probable sarcopenia in community-dwelling older adults. Nutrients. 2023;15(6):1505. doi: 10.3390/nu15061505. DOI: https://doi.org/10.3390/nu15061505
Tomasiewicz A, Polański J, Tański W. Advancing the understanding of malnutrition in the elderly population: Current insights and future directions. Nutrients. 2024;16(15):2502. doi: 10.3390/nu16152502. DOI: https://doi.org/10.3390/nu16152502
Nowak J, Jabczyk M, Skrzypek M, Brukało K, Bartosiewicz A, Hudzik B, et al. Comparison of body mass index range criteria and their association with nutrition-related risk: A cross-sectional study in Polish older adults. Med Sci Monit. 2025;31:e948384. doi: 10.12659/MSM.948384. DOI: https://doi.org/10.12659/MSM.948384
Norman K, Haß U, Pirlich M. Malnutrition in older adults-recent advances and remaining challenges. Nutrients. 2021;13(8):2764. doi: 10.3390/nu13082764. DOI: https://doi.org/10.3390/nu13082764
Ahmed T, Haboubi N. Assessment and management of nutrition in older people and its importance to health. Clin Interv Aging. 2010;5:207-216. doi: 10.2147/cia.s9664. DOI: https://doi.org/10.2147/CIA.S9664
Shigehara K, Kato Y, Izumi K, Mizokami A. Relationship between testosterone and sarcopenia in older-adult men: A narrative review. J Clin Med. 2022;11(20):6202. doi: 10.3390/jcm11206202. DOI: https://doi.org/10.3390/jcm11206202
Huang YF, Liu SP, Muo CH, Lai CY, Chang CT. Male sex and ageing are independent risk factors for sarcopenia stage in patients with chronic kidney disease not yet on dialysis. J Cachexia Sarcopenia Muscle. 2024;15(6):2684-2692. doi: 10.1002/jcsm.13612. DOI: https://doi.org/10.1002/jcsm.13612
Meng X, Wang Z, Lyu L. Bidirectional association between sarcopenia and depression: A systematic review and meta-analysis. Arch Gerontol Geriatr. 2025;132:105787. doi: 10.1016/j.archger.2025.105787. DOI: https://doi.org/10.1016/j.archger.2025.105787
Li Z, Liu B, Tong X, Ma Y, Bao T, Yue J, et al. The association between sarcopenia and incident of depressive symptoms: a prospective cohort study. BMC Geriatr. 2024;24(1):74. doi: 10.1186/s12877-023-04653-z. DOI: https://doi.org/10.1186/s12877-023-04653-z
Shiba T, Sato R, Sawaya Y, Hirose T, Ishizaka M, Kubo A, et al. Sarcopenia with depression presents a more severe disability than only sarcopenia among Japanese older adults in need of long-term care. Medicina (Kaunas). 2023;59(6):1095. doi: 10.3390/medicina59061095. DOI: https://doi.org/10.3390/medicina59061095
Park YS, Yoo K, Kim HJ, Kim M, Won CW. Association between sarcopenia components and depressed mood varies by sex among community-dwelling older adults from the Korean frailty and aging cohort study. Sci Rep. 2025;15(1):3987. doi: 10.1038/s41598-025-88437-y. DOI: https://doi.org/10.1038/s41598-025-88437-y
Zhong Q, Jiang L, An K, Zhang L, Li S, An Z. Depression and risk of sarcopenia: a national cohort and Mendelian randomization study. Front Psychiatry. 2023;14:1263553. doi: 10.3389/fpsyt.2023.1263553. DOI: https://doi.org/10.3389/fpsyt.2023.1263553
Li Z, Tong X, Ma Y, Bao T, Yue J. Prevalence of depression in patients with sarcopenia and correlation between the two diseases: systematic review and meta-analysis. J Cachexia Sarcopenia Muscle. 2022;13(1):128-144. doi: 10.1002/jcsm.12908. DOI: https://doi.org/10.1002/jcsm.12908
Zhang HY, Chong MC, Tan MP, Chua YP, Zhang JH. The association between depressive symptoms and sarcopenia among community-dwelling older adults: A cross-sectional study. J Multidiscip Healthc. 2022;15:837-846. doi: 10.2147/JMDH.S355680. DOI: https://doi.org/10.2147/JMDH.S355680
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 )

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Published by Al-Rafidain University College. This is an open access journal issued under the CC BY-NC-SA 4.0 license (https://creativecommons.org/licenses/by-nc-sa/4.0/).



